Provisional. Ranked October 7, 2026 from the filings the IRS had published by then. Organizations have up to 10½ months after their year ends to file, so the list will change as the rest arrive.
| Rank | National | Organization | Growth | Revenue |
|---|---|---|---|---|
| 1 | 339 | Lowcountry Land Trust INC Charleston, SC · Environment | 512% | $2.0M → $12.4M |
| 2 | 352 | Boys and Girls Clubs of York County Rock Hill, SC · Youth development | 496% | $738K → $4.4M |
| 3 | 429 | National Medal of Honor Center for MT Pleasant, SC · Philanthropy | 423% | $1.2M → $6.4M |
| 4 | 516 | Operation Patriots Fob INC Bluffton, SC · Philanthropy | 361% | $530K → $2.4M |
| 5 | 556 | The Original Six Foundation Columbia, SC · Community improvement | 345% | $548K → $2.4M |
| 6 | 581 | Myrtle Beach Downtown Alliance Inc Myrtle Beach, SC · Community improvement | 333% | $593K → $2.6M |
| 7 | 641 | ST Lukes Free Medical Clinic of Spartanburg, SC · Health care | 305% | $835K → $3.4M |
| 8 | 652 | Urban League of the Upstate Greenville, SC · Human services | 302% | $1.1M → $4.4M |
| 9 | 685 | Serve and Connect Columbia, SC · Human services | 293% | $539K → $2.1M |
| 10 | 725 | Center of Excellence for Educator Preparation and Innovation INC Columbia, SC · Education | 279% | $2.1M → $8.1M |
| 11 | 759 | Ronald Mcdonald House Charities of Charleston, SC · Health care | 269% | $2.1M → $7.8M |
| 12 | 819 | Palmetto Trail Columbia, SC · Environment | 251% | $827K → $2.9M |
| 13 | 867 | Lincoln High School Preservation Al Sumter, SC · Education | 241% | $614K → $2.1M |
| 14 | 977 | Association for the Blind and Charleston, SC | 220% | $835K → $2.7M |